Manchester United moved back into the top four after beating Southampton, while the north London derby ended in a draw.
Pierre-Emerick Aubameyang saw a last-gasp penalty saved as Arsenal drew 1-1 against Tottenham to leave Spurs four points ahead of their north London rivals in the top-four race.
Aaron Ramsey, playing in his final north London derby before leaving to join Juventus in the summer, finished on the counter-attack after 16 minutes to put the Gunners ahead.
Spurs levelled from the penalty spot in the 74th minute through Harry Kane after he had been barged over by Shkodran Mustafi.
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